1005288-15-2
1005288-15-2 structure
- Name: β-catenin inhibitor C2
- Chemical Name: β-catenin inhibitor C2
- CAS Number: 1005288-15-2
- Molecular Formula: C19H20Br2N2Os
- Molecular Weight: 484.25
- Catalog: Signaling Pathways Stem Cell/Wnt Wnt
- Create Date: 2022-07-11 10:26:12
- Modify Date: 2024-01-05 18:05:45
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β-catenin inhibitor C2 is a novel potent selective β-catenin inhibitor with Kd of 54.96 nM, directly to ARM domain of β-catenin.β-catenin inhibitor C2 reduced viability of DLD1 and SW480 cells in dose-dependent manner with IC50 ranging between 0.8-1.3 uM, viability of HCT116 and SW48 with IC50 3.45-5.35 uM.β-catenin inhibitor C2 selectively inhibits β-catenin, lowers its cellular load and significantly reduces viability of β-catenin-driven cancer cells.
| Name | β-catenin inhibitor C2 |
|---|
| Description | β-catenin inhibitor C2 is a novel potent selective β-catenin inhibitor with Kd of 54.96 nM, directly to ARM domain of β-catenin.β-catenin inhibitor C2 reduced viability of DLD1 and SW480 cells in dose-dependent manner with IC50 ranging between 0.8-1.3 uM, viability of HCT116 and SW48 with IC50 3.45-5.35 uM.β-catenin inhibitor C2 selectively inhibits β-catenin, lowers its cellular load and significantly reduces viability of β-catenin-driven cancer cells. |
|---|---|
| References | 1. Anton Cheltsov, et al. Sci Rep. 2020 May 15;10(1):8096. |
| Molecular Formula | C19H20Br2N2Os |
|---|---|
| Molecular Weight | 484.25 |