1313759-88-4
1313759-88-4 structure
- Name: CJ-1639
- Chemical Name: CJ-1639
- CAS Number: 1313759-88-4
- Molecular Formula: C27H34N4O2S
- Molecular Weight: 478.655
- Create Date: 2022-08-18 20:05:59
- Modify Date: 2023-10-20 10:34:26
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CJ-1639 (CJ1639) is a potent, highly selective dopamine D3 receptor (D3R) full agonist with Ki of 0.5 nM, >5,000-fold selectivity over D1 and D2 receptors in binding assays.CJ-1639 binds to human D3 receptor with a K(i) value of 3.61 nM and displays over >1000-fold selectivity over human D1 and D2 receptors.CJ-1639 is an excellent pharmacological tool to elucidate the role of the D3 receptor in different neurological conditions in animal models.
| Name | CJ-1639 |
|---|
| Description | CJ-1639 (CJ1639) is a potent, highly selective dopamine D3 receptor (D3R) full agonist with Ki of 0.5 nM, >5,000-fold selectivity over D1 and D2 receptors in binding assays.CJ-1639 binds to human D3 receptor with a K(i) value of 3.61 nM and displays over >1000-fold selectivity over human D1 and D2 receptors.CJ-1639 is an excellent pharmacological tool to elucidate the role of the D3 receptor in different neurological conditions in animal models. |
|---|---|
| References | 1. Jianyong Chen, et al. ACS Med Chem Lett. 2011 Aug 11;2(8):620-625. |
| Molecular Formula | C27H34N4O2S |
|---|---|
| Molecular Weight | 478.655 |