2250287-34-2
2250287-34-2 structure
- Name: JWD-065
- Chemical Name: JWD-065
- CAS Number: 2250287-34-2
- Molecular Formula: C24H26N6O2S
- Molecular Weight: 462.572
- Create Date: 2022-07-01 19:35:39
- Modify Date: 2024-08-15 13:34:19
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JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM.
| Name | JWD-065 |
|---|
| Description | JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM. |
|---|---|
| References | 1. Sebum Lee, et al. Neuron. 2016, 91(1), 41-55. 2. Miduturu CV et al. Chem Biol. 2011;18:868–879. |
| Molecular Formula | C24H26N6O2S |
|---|---|
| Molecular Weight | 462.572 |