- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: NH4-6
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Huang
- DC Chemicals Limited
- China
- Product Name: NH4-6
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
2375182-58-2
2375182-58-2 structure
- Name: NH4-6
- Chemical Name: NH4-6
- CAS Number: 2375182-58-2
- Molecular Formula: C33H59In4O3S
- Molecular Weight: 718.824
- Create Date: 2022-07-31 13:06:26
- Modify Date: 2023-01-14 01:13:17
-
NH4-6 is a potent, selective pan SIRT1-3 inhibitor with IC50 of 3.0/0.032/2.3 uM for SIRT1/2/3, respectively.NH4-6 does not inhibits SIRT5 and SIRT6.NH4-6 (30 mg/kg) significantly impaired tumor growth in HCT-116 tumor xenograft.
| Name | NH4-6 |
|---|
| Description | NH4-6 is a potent, selective pan SIRT1-3 inhibitor with IC50 of 3.0/0.032/2.3 uM for SIRT1/2/3, respectively.NH4-6 does not inhibits SIRT5 and SIRT6.NH4-6 (30 mg/kg) significantly impaired tumor growth in HCT-116 tumor xenograft. |
|---|---|
| References | 1. Jun Young Hong, et al. ACS Chem Biol. 2021 Jul 16;16(7):1266-1275. |
| Molecular Formula | C33H59In4O3S |
|---|---|
| Molecular Weight | 718.824 |