2375182-58-2

2375182-58-2 structure
2375182-58-2 structure
  • Name: NH4-6
  • Chemical Name: NH4-6
  • CAS Number: 2375182-58-2
  • Molecular Formula: C33H59In4O3S
  • Molecular Weight: 718.824
  • Create Date: 2022-07-31 13:06:26
  • Modify Date: 2023-01-14 01:13:17
  • NH4-6 is a potent, selective pan SIRT1-3 inhibitor with IC50 of 3.0/0.032/2.3 uM for SIRT1/2/3, respectively.NH4-6 does not inhibits SIRT5 and SIRT6.NH4-6 (30 mg/kg) significantly impaired tumor growth in HCT-116 tumor xenograft.

Name NH4-6
Description NH4-6 is a potent, selective pan SIRT1-3 inhibitor with IC50 of 3.0/0.032/2.3 uM for SIRT1/2/3, respectively.NH4-6 does not inhibits SIRT5 and SIRT6.NH4-6 (30 mg/kg) significantly impaired tumor growth in HCT-116 tumor xenograft.
References 1. Jun Young Hong, et al. ACS Chem Biol. 2021 Jul 16;16(7):1266-1275.
Molecular Formula C33H59In4O3S
Molecular Weight 718.824
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