241825-16-1
241825-16-1 structure
- Name: KYT-1
- Chemical Name: KYT-1
- CAS Number: 241825-16-1
- Molecular Formula: C29H49N9O6
- Molecular Weight: 619.768
- Create Date: 2022-07-11 14:38:51
- Modify Date: 2024-09-08 12:04:59
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KYT-1 is a potent, selective inhibitor of P. gingivalis virulence factor Arg-gingipain (Rgp) with Ki 40 nM (RgpA/B).KYT-1 showed significant inhibitory effects on SMC proliferation stimulated by Porphyromonas gingivalis.
| Name | KYT-1 |
|---|
| Description | KYT-1 is a potent, selective inhibitor of P. gingivalis virulence factor Arg-gingipain (Rgp) with Ki 40 nM (RgpA/B).KYT-1 showed significant inhibitory effects on SMC proliferation stimulated by Porphyromonas gingivalis. |
|---|---|
| References | 1. Kadowaki T, et al. Mol Pharmacol. 2004 Dec;66(6):1599-606. 2. Hosn KN, et al. Clin Exp Dent Res. 2015 Oct 27;1(1):18-25. 3. Inaba H, et al. J Periodontol. 2011 Nov;82(11):1616-22. 4. Cao C, et al. Int J Clin Exp Med. 2015 Oct 15;8(10):18327-34. |
| Molecular Formula | C29H49N9O6 |
|---|---|
| Molecular Weight | 619.768 |