739301-85-0
739301-85-0 structure
- Name: NSC45586 free base
- Chemical Name: NSC45586 free base
- CAS Number: 739301-85-0
- Molecular Formula: C20H18N6O3
- Molecular Weight: 390.403
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Ser/Thr Protease
- Create Date: 2022-07-02 06:26:39
- Modify Date: 2024-01-13 12:54:08
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NSC45586 free base (NCS 45586, NCI45586) is a potent, specific PHLPP2 inhibitor with IC50 of 4 uM, targets the PHLPP2 PP2C domain, suppresses MYC and triggers cell death.
| Name | NSC45586 free base |
|---|
| Description | NSC45586 free base (NCS 45586, NCI45586) is a potent, specific PHLPP2 inhibitor with IC50 of 4 uM, targets the PHLPP2 PP2C domain, suppresses MYC and triggers cell death. |
|---|---|
| References | 1. Nowak DG, et al. J Cell Biol. 2019 May 15. pii: jcb.201902048. doi: 10.1083/jcb.201902048. |
| Molecular Formula | C20H18N6O3 |
|---|---|
| Molecular Weight | 390.403 |