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329693-22-3

329693-22-3 structure

329693-22-3 structure

Name: A1AR antagonist 6
Chemical Name: A1AR antagonist 6
CAS Number: 329693-22-3
Molecular Formula: C₁₇H₁₅N₃O₂
Molecular Weight: 293.32
Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
Create Date: 2022-07-02 08:19:16
Modify Date: 2024-01-12 09:58:46
A1AR antagonist 6 (compound 15) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 6.38 and a pKi of 7.13[1].

Name	A1AR antagonist 6

Description	A1AR antagonist 6 (compound 15) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 6.38 and a pKi of 7.13[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	hA1AR:7.13 (pKi) hA2AAR:<4 (pKi)
References	[1]. Wei Y, et al. Identification of new potent A1 adenosine receptor antagonists using a multistage virtual screening approach. Eur J Med Chem. 2020 Feb 1;187:111936.

Molecular Formula	C₁₇H₁₅N₃O₂
Molecular Weight	293.32

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