A1AR antagonist 6

Modify Date: 2024-01-12 09:58:46

A1AR antagonist 6 Structure
A1AR antagonist 6 structure
Common Name A1AR antagonist 6
CAS Number 329693-22-3 Molecular Weight 293.32
Density N/A Boiling Point N/A
Molecular Formula C17H15N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A1AR antagonist 6


A1AR antagonist 6 (compound 15) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 6.38 and a pKi of 7.13[1].

 Names

Name A1AR antagonist 6

 A1AR antagonist 6 Biological Activity

Description A1AR antagonist 6 (compound 15) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 6.38 and a pKi of 7.13[1].
Related Catalog
Target

hA1AR:7.13 (pKi)

hA2AAR:<4 (pKi)

References

[1]. Wei Y, et al. Identification of new potent A1 adenosine receptor antagonists using a multistage virtual screening approach. Eur J Med Chem. 2020 Feb 1;187:111936.

 Chemical & Physical Properties

Molecular Formula C17H15N3O2
Molecular Weight 293.32