2421120-96-7

2421120-96-7 structure

Name: AChE/BChE-IN-8
Chemical Name: AChE/BChE-IN-8
CAS Number: 2421120-96-7
Molecular Formula: C₂₆H₃₂N₂O₂
Molecular Weight: 404.54
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2022-07-01 20:41:46
Modify Date: 2024-01-10 07:10:54
AChE/BChE-IN-8 (Compound 5a) is an uncompetitive AChE and mixed BChE inhibitor with Ki values of 0.788 μM and 2.364 μM against Electrophorus electricus AChE (EeAChE) and equine BChE (eqBChE), respectively. AChE/BChE-IN-8 can cross the BBB and has low cytotoxicity[1].

Name	AChE/BChE-IN-8

Description	AChE/BChE-IN-8 (Compound 5a) is an uncompetitive AChE and mixed BChE inhibitor with Ki values of 0.788 μM and 2.364 μM against Electrophorus electricus AChE (EeAChE) and equine BChE (eqBChE), respectively. AChE/BChE-IN-8 can cross the BBB and has low cytotoxicity[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	Ki: 0.788 μM (EeAChE), 2.364 μM (eqBChE)[1]
References	[1]. Bortolami M, et al. New deferiprone derivatives as multi-functional cholinesterase inhibitors: design, synthesis and in vitro evaluation. Eur J Med Chem. 2020 Jul 15;198:112350.

Molecular Formula	C₂₆H₃₂N₂O₂
Molecular Weight	404.54