AChE/BChE-IN-8

Modify Date: 2024-01-10 07:10:54

AChE/BChE-IN-8 structure	Common Name	AChE/BChE-IN-8
	CAS Number	2421120-96-7	Molecular Weight	404.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₂N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AChE/BChE-IN-8

AChE/BChE-IN-8 (Compound 5a) is an uncompetitive AChE and mixed BChE inhibitor with Ki values of 0.788 μM and 2.364 μM against Electrophorus electricus AChE (EeAChE) and equine BChE (eqBChE), respectively. AChE/BChE-IN-8 can cross the BBB and has low cytotoxicity[1].

Name	AChE/BChE-IN-8

Description	AChE/BChE-IN-8 (Compound 5a) is an uncompetitive AChE and mixed BChE inhibitor with Ki values of 0.788 μM and 2.364 μM against Electrophorus electricus AChE (EeAChE) and equine BChE (eqBChE), respectively. AChE/BChE-IN-8 can cross the BBB and has low cytotoxicity[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	Ki: 0.788 μM (EeAChE), 2.364 μM (eqBChE)[1]
References	[1]. Bortolami M, et al. New deferiprone derivatives as multi-functional cholinesterase inhibitors: design, synthesis and in vitro evaluation. Eur J Med Chem. 2020 Jul 15;198:112350.

Molecular Formula	C₂₆H₃₂N₂O₂
Molecular Weight	404.54

AChE/BChE-IN-8

Use of AChE/BChE-IN-8

Names

AChE/BChE-IN-8 Biological Activity

Chemical & Physical Properties