AChE/BChE-IN-8

Modify Date: 2024-01-10 07:10:54

AChE/BChE-IN-8 Structure
AChE/BChE-IN-8 structure
Common Name AChE/BChE-IN-8
CAS Number 2421120-96-7 Molecular Weight 404.54
Density N/A Boiling Point N/A
Molecular Formula C26H32N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AChE/BChE-IN-8


AChE/BChE-IN-8 (Compound 5a) is an uncompetitive AChE and mixed BChE inhibitor with Ki values of 0.788 μM and 2.364 μM against Electrophorus electricus AChE (EeAChE) and equine BChE (eqBChE), respectively. AChE/BChE-IN-8 can cross the BBB and has low cytotoxicity[1].

 Names

Name AChE/BChE-IN-8

 AChE/BChE-IN-8 Biological Activity

Description AChE/BChE-IN-8 (Compound 5a) is an uncompetitive AChE and mixed BChE inhibitor with Ki values of 0.788 μM and 2.364 μM against Electrophorus electricus AChE (EeAChE) and equine BChE (eqBChE), respectively. AChE/BChE-IN-8 can cross the BBB and has low cytotoxicity[1].
Related Catalog
Target

Ki: 0.788 μM (EeAChE), 2.364 μM (eqBChE)[1]

References

[1]. Bortolami M, et al. New deferiprone derivatives as multi-functional cholinesterase inhibitors: design, synthesis and in vitro evaluation. Eur J Med Chem. 2020 Jul 15;198:112350.

 Chemical & Physical Properties

Molecular Formula C26H32N2O2
Molecular Weight 404.54
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