407587-01-3
407587-01-3 structure
- Name: ANO1-IN-1
- Chemical Name: ANO1-IN-1
- CAS Number: 407587-01-3
- Molecular Formula: C18H28N2O2S
- Molecular Weight: 336.49
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Chloride Channel
- Create Date: 2022-06-26 12:01:35
- Modify Date: 2025-08-24 14:57:52
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ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC50 of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells[1].
| Name | ANO1-IN-1 |
|---|
| Description | ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC50 of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2.56 μM (ANO1), 15.43 μM (ANO2)[1] |
| In Vitro | ANO1-IN-1 (Compound 9c) (10 μM) significantly suppresses migration and invasion of U251 cells[1]. ANO1-IN-1 and TMZ combination brings about remarkable synergistic effects in suppressing proliferation of GBM cells[1]. |
| References |
| Molecular Formula | C18H28N2O2S |
|---|---|
| Molecular Weight | 336.49 |