ANO1-IN-1
Modify Date: 2025-08-24 14:57:52
ANO1-IN-1 structure
|
Common Name | ANO1-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 407587-01-3 | Molecular Weight | 336.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H28N2O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ANO1-IN-1ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC50 of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells[1]. |
| Name | ANO1-IN-1 |
|---|
| Description | ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC50 of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2.56 μM (ANO1), 15.43 μM (ANO2)[1] |
| In Vitro | ANO1-IN-1 (Compound 9c) (10 μM) significantly suppresses migration and invasion of U251 cells[1]. ANO1-IN-1 and TMZ combination brings about remarkable synergistic effects in suppressing proliferation of GBM cells[1]. |
| References |
| Molecular Formula | C18H28N2O2S |
|---|---|
| Molecular Weight | 336.49 |
| InChIKey | QJDASIZKRQHFFS-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C(=O)Nc1sc2c(c1C(N)=O)CCC(C(C)(C)C)C2 |