2127403-65-8

2127403-65-8 structure

Name: Anti-inflammatory agent 20
Chemical Name: Anti-inflammatory agent 20
CAS Number: 2127403-65-8
Molecular Formula: C₃₉H₆₆N₂O₈
Molecular Weight: 690.95
Catalog: Signaling Pathways Immunology/Inflammation COX
Create Date: 2022-07-02 06:04:36
Modify Date: 2025-08-25 12:00:33
Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation[1].

Name	Anti-inflammatory agent 20

Description	Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	NF-κB COX-2 TNF-α
References	[1]. Yang G, et al. Design, synthesis and anti-inflammatory activity of 3-amino acid derivatives of ocotillol-type sapogenins. Eur J Med Chem. 2020 Sep 15;202:112507.

Molecular Formula	C₃₉H₆₆N₂O₈
Molecular Weight	690.95