2387506-35-4

2387506-35-4 structure

Name: Anti-MI/R injury agent 1
Chemical Name: Anti-MI/R injury agent 1
CAS Number: 2387506-35-4
Molecular Formula: C₃₂H₄₉NO₆
Molecular Weight: 543.73
Catalog: Research Areas Cardiovascular Disease
Create Date: 2022-07-02 06:26:31
Modify Date: 2024-01-12 10:34:52
Anti-MI/R injury agent 1 (compound 18), a Panaxatriol derivative, is an orally active, potent anti-myocardial ischemia/reperfusion (anti-MI/R) injury agent. Anti-MI/R injury agent 1 enhances oxygen-glucose deprivation and reperfusion (OGD/R)-induced cardiomyocyte injury cell viability. Anti-MI/R injury agent 1 can markedly reduce myocardial infarction size, decrease circulating cardiac troponin I (cTnI) leakage, and alleviate cardiac tissue damage in the rats[1].

Name	Anti-MI/R injury agent 1

Description	Anti-MI/R injury agent 1 (compound 18), a Panaxatriol derivative, is an orally active, potent anti-myocardial ischemia/reperfusion (anti-MI/R) injury agent. Anti-MI/R injury agent 1 enhances oxygen-glucose deprivation and reperfusion (OGD/R)-induced cardiomyocyte injury cell viability. Anti-MI/R injury agent 1 can markedly reduce myocardial infarction size, decrease circulating cardiac troponin I (cTnI) leakage, and alleviate cardiac tissue damage in the rats[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Qiong Wu, et al. Synthesis and biological evaluation of panaxatriol derivatives against myocardial ischemia/reperfusion injury in the rat. Eur J Med Chem. 2020 Jan 1;185:111729.

Molecular Formula	C₃₂H₄₉NO₆
Molecular Weight	543.73