Anti-MI/R injury agent 1

Modify Date: 2024-01-12 10:34:52

Anti-MI/R injury agent 1 Structure
Anti-MI/R injury agent 1 structure
Common Name Anti-MI/R injury agent 1
CAS Number 2387506-35-4 Molecular Weight 543.73
Density N/A Boiling Point N/A
Molecular Formula C32H49NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anti-MI/R injury agent 1


Anti-MI/R injury agent 1 (compound 18), a Panaxatriol derivative, is an orally active, potent anti-myocardial ischemia/reperfusion (anti-MI/R) injury agent. Anti-MI/R injury agent 1 enhances oxygen-glucose deprivation and reperfusion (OGD/R)-induced cardiomyocyte injury cell viability. Anti-MI/R injury agent 1 can markedly reduce myocardial infarction size, decrease circulating cardiac troponin I (cTnI) leakage, and alleviate cardiac tissue damage in the rats[1].

 Names

Name Anti-MI/R injury agent 1

 Anti-MI/R injury agent 1 Biological Activity

Description Anti-MI/R injury agent 1 (compound 18), a Panaxatriol derivative, is an orally active, potent anti-myocardial ischemia/reperfusion (anti-MI/R) injury agent. Anti-MI/R injury agent 1 enhances oxygen-glucose deprivation and reperfusion (OGD/R)-induced cardiomyocyte injury cell viability. Anti-MI/R injury agent 1 can markedly reduce myocardial infarction size, decrease circulating cardiac troponin I (cTnI) leakage, and alleviate cardiac tissue damage in the rats[1].
Related Catalog
References

[1]. Qiong Wu, et al. Synthesis and biological evaluation of panaxatriol derivatives against myocardial ischemia/reperfusion injury in the rat. Eur J Med Chem. 2020 Jan 1;185:111729.

 Chemical & Physical Properties

Molecular Formula C32H49NO6
Molecular Weight 543.73