2422019-91-6

2422019-91-6 structure

Name: Antifungal agent 30
Chemical Name: Antifungal agent 30
CAS Number: 2422019-91-6
Molecular Formula: C₁₈H₁₄Cl₂F₂N₂Se
Molecular Weight: 446.18
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2022-07-02 01:34:23
Modify Date: 2024-01-15 16:22:01
Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51[1].

Name	Antifungal agent 30

Description	Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Xu H, et al. Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents. Eur J Med Chem. 2020 Jul 15;198:112360.

Molecular Formula	C₁₈H₁₄Cl₂F₂N₂Se
Molecular Weight	446.18