Antifungal agent 30

Modify Date: 2024-01-15 16:22:01

Antifungal agent 30 Structure
Antifungal agent 30 structure
Common Name Antifungal agent 30
CAS Number 2422019-91-6 Molecular Weight 446.18
Density N/A Boiling Point N/A
Molecular Formula C18H14Cl2F2N2Se Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antifungal agent 30


Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51[1].

 Names

Name Antifungal agent 30

 Antifungal agent 30 Biological Activity

Description Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51[1].
Related Catalog
References

[1]. Xu H, et al. Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents. Eur J Med Chem. 2020 Jul 15;198:112360.

 Chemical & Physical Properties

Molecular Formula C18H14Cl2F2N2Se
Molecular Weight 446.18