2409952-04-9

2409952-04-9 structure

Name: Antitumor agent-59
Chemical Name: Antitumor agent-59
CAS Number: 2409952-04-9
Molecular Formula: C₄₃H₃₆F₂N₆O₆
Molecular Weight: 770.78
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-07-02 05:37:56
Modify Date: 2025-08-27 09:09:19
Antitumor agent-59 (Compound 13b) is a potent antitumor agent. Antitumor agent-59 effectively inhibits the proliferation and migration of HCT116 cells. Antitumor agent-59 induces HCT116 cell apoptosis and arrests the cell cycle at the G2/M phase[1].

Name	Antitumor agent-59

Description	Antitumor agent-59 (Compound 13b) is a potent antitumor agent. Antitumor agent-59 effectively inhibits the proliferation and migration of HCT116 cells. Antitumor agent-59 induces HCT116 cell apoptosis and arrests the cell cycle at the G2/M phase[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Antitumor agent-59 (Compound 13b) (72 h) shows antitumor activities with IC50 values of 0.032 ± 0.0071, 0.20 ± 0.020, 0.73 ± 0.12 and 0.58 ± 0.15 μM against HCT116, MCF-7, A549 and HUVEC cells, respectively[1].
References	[1]. Liang H, et al. Discovery of novel bis-evodiamine derivatives with potent antitumor activity. Bioorg Med Chem. 2022 Jul 1;65:116793.

Molecular Formula	C₄₃H₃₆F₂N₆O₆
Molecular Weight	770.78