2460735-29-7

2460735-29-7 structure

Name: Antitumor agent-62
Chemical Name: Antitumor agent-62
CAS Number: 2460735-29-7
Molecular Formula: C₂₁H₁₉N₃O₉S
Molecular Weight: 489.46
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-06-30 16:55:56
Modify Date: 2024-01-08 20:30:31
Antitumor agent-62 (Compound 47) is a NO-releasing antitumor agent. Antitumor agent-62 shows antiproliferative activity against four cancer cell lines. Antitumor agent-62 activates mitochondrial apoptosis pathway and arrests cell cycle at G2/M phase[1].

Name	Antitumor agent-62

Description	Antitumor agent-62 (Compound 47) is a NO-releasing antitumor agent. Antitumor agent-62 shows antiproliferative activity against four cancer cell lines. Antitumor agent-62 activates mitochondrial apoptosis pathway and arrests cell cycle at G2/M phase[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Antitumor agent-62 (Compound 47) shows antiproliferative activity with IC50 values of 1.23 ± 0.10, 1.91 ± 0.14, 2.81 ± 0.13, 4.18 ± 0.15 and 9.16 ± 0.38 μM against MDA-MB-231, MCF-7, HepG2, A549 and LO2 cells, respectively[1].
References	[1]. Shi Z, et al. Novel NO-releasing scopoletin derivatives induce cell death via mitochondrial apoptosis pathway and cell cycle arrest. Eur J Med Chem. 2020 Aug 15;200:112386.

Molecular Formula	C₂₁H₁₉N₃O₉S
Molecular Weight	489.46