1627600-90-1

1627600-90-1 structure
1627600-90-1 structure
  • Name: Antitumor agent-63
  • Chemical Name: Antitumor agent-63
  • CAS Number: 1627600-90-1
  • Molecular Formula: C38H46N4O18
  • Molecular Weight: 846.79
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Topoisomerase
  • Create Date: 2022-07-01 09:07:41
  • Modify Date: 2025-08-25 20:49:15
  • Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition[1].

Name Antitumor agent-63
Description Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition[1].
Related Catalog
Target

Top1

In Vitro Antitumor agent-63 (Compound 40) shows cytotoxicity activities with IC50 values of 1.2, 0.8, 30.5 and >100 µM against HepG2, HCT-116, SW1990 and HEK-293, respectively[1].
References

[1]. Li M, et al. Oligosaccharide-camptothecin conjugates as potential antineoplastic drugs: Design, synthesis and biological evaluation. Eur J Med Chem. 2020 Sep 15;202:112509.

Molecular Formula C38H46N4O18
Molecular Weight 846.79
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.