Antitumor agent-63

Modify Date: 2025-08-25 20:49:15

Antitumor agent-63 Structure
Antitumor agent-63 structure
Common Name Antitumor agent-63
CAS Number 1627600-90-1 Molecular Weight 846.79
Density N/A Boiling Point N/A
Molecular Formula C38H46N4O18 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antitumor agent-63


Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition[1].

 Names

Name Antitumor agent-63

 Antitumor agent-63 Biological Activity

Description Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition[1].
Related Catalog
Target

Top1

In Vitro Antitumor agent-63 (Compound 40) shows cytotoxicity activities with IC50 values of 1.2, 0.8, 30.5 and >100 µM against HepG2, HCT-116, SW1990 and HEK-293, respectively[1].
References

[1]. Li M, et al. Oligosaccharide-camptothecin conjugates as potential antineoplastic drugs: Design, synthesis and biological evaluation. Eur J Med Chem. 2020 Sep 15;202:112509.

 Chemical & Physical Properties

Molecular Formula C38H46N4O18
Molecular Weight 846.79
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