2691937-01-4

2691937-01-4 structure

2691937-01-4 structure

Name: ATX inhibitor 19
Chemical Name: ATX inhibitor 19
CAS Number: 2691937-01-4
Molecular Formula: C₂₈H₃₃ClN₆O₂S
Molecular Weight: 553.12
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2022-07-11 10:04:01
Modify Date: 2024-01-24 15:37:44
ATX inhibitor 19 (compound 22) is a potent ATX (autotaxin) inhibitor, with an IC50 of 156 nM[1].

Name	ATX inhibitor 19

Description	ATX inhibitor 19 (compound 22) is a potent ATX (autotaxin) inhibitor, with an IC50 of 156 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Target	Autotaxin:156 ± 19.8 nM (IC50)
References	[1]. Jia F, et al. Structure-based linker exploration: Discovery of 1-ethyl-1H-indole analogs as novel ATX inhibitors. Bioorg Med Chem. 2020 Nov 15;28(22):115795.

Molecular Formula	C₂₈H₃₃ClN₆O₂S
Molecular Weight	553.12