2691937-03-6

2691937-03-6 structure

2691937-03-6 structure

Name: ATX inhibitor 20
Chemical Name: ATX inhibitor 20
CAS Number: 2691937-03-6
Molecular Formula: C₃₁H₃₄FN₅O₃
Molecular Weight: 543.63
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2022-07-23 13:23:02
Modify Date: 2024-01-12 00:27:34
ATX inhibitor 20 (compound 24) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.3 nM[1].

Name	ATX inhibitor 20

Description	ATX inhibitor 20 (compound 24) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.3 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Target	Autotaxin:2.3 ± 0.31 nM (IC50)
References	[1]. Jia F, et al. Structure-based linker exploration: Discovery of 1-ethyl-1H-indole analogs as novel ATX inhibitors. Bioorg Med Chem. 2020 Nov 15;28(22):115795.

Molecular Formula	C₃₁H₃₄FN₅O₃
Molecular Weight	543.63