2477606-97-4

2477606-97-4 structure

Name: Aβ-IN-4
Chemical Name: Aβ-IN-4
CAS Number: 2477606-97-4
Molecular Formula: C₃₃H₄₃N₅O₇
Molecular Weight: 621.72
Catalog: Research Areas Neurological Disease
Create Date: 2022-07-01 19:43:54
Modify Date: 2024-01-03 18:23:45
Aβ-IN-4 (compound 12) is a potent amyloid β (Aβ) inhibitor. Aβ-IN-4 inhibits Aβ42 aggregation. However, Aβ-IN-4 can not alleviate the neurotoxicity of Aβ42 in SH-SY5Y cells. Aβ-IN-4 can not change the aggregation state of Aβ42 into a nontoxic one[1].

Name	Aβ-IN-4

Description	Aβ-IN-4 (compound 12) is a potent amyloid β (Aβ) inhibitor. Aβ-IN-4 inhibits Aβ42 aggregation. However, Aβ-IN-4 can not alleviate the neurotoxicity of Aβ42 in SH-SY5Y cells. Aβ-IN-4 can not change the aggregation state of Aβ42 into a nontoxic one[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Tanaka F, et al. Design and synthesis of β-strand-fixed peptides inhibiting aggregation of amyloid β-protein. Bioorg Med Chem. 2020 Sep 15;28(18):115676.

Molecular Formula	C₃₃H₄₃N₅O₇
Molecular Weight	621.72