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2259640-87-2

2259640-87-2 structure

2259640-87-2 structure

Name: CBP/p300-IN-17
Chemical Name: CBP/p300-IN-17
CAS Number: 2259640-87-2
Molecular Formula: C₂₅H₂₈N₄O₃
Molecular Weight: 432.51
Catalog: Signaling Pathways Epigenetics Histone Acetyltransferase
Create Date: 2022-07-01 19:41:50
Modify Date: 2024-07-16 18:37:42
CBP/p300-IN-17 (compound 7) is a potent EP300/CBP HAT inhibitor with IC50s of 0.18, 0.69 µM for HAT EP300 and LK2 H3K27, respectively[1].

Name	CBP/p300-IN-17

Description	CBP/p300-IN-17 (compound 7) is a potent EP300/CBP HAT inhibitor with IC50s of 0.18, 0.69 µM for HAT EP300 and LK2 H3K27, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Acetyltransferase
Target	EP300:0.18 μM (IC50) LK2 H3K27:0.69 μM (IC50)
References	[1]. Kanada R, et al. Discovery of EP300/CBP histone acetyltransferase inhibitors through scaffold hopping of 1,4-oxazepane ring. Bioorg Med Chem Lett. 2022 Jun 15;66:128726.

Molecular Formula	C₂₅H₂₈N₄O₃
Molecular Weight	432.51

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