2091883-59-7

2091883-59-7 structure
2091883-59-7 structure
  • Name: Dyrk1A-IN-4
  • Chemical Name: Dyrk1A-IN-4
  • CAS Number: 2091883-59-7
  • Molecular Formula: C14H13F3N6
  • Molecular Weight: 322.29
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK DYRK
  • Create Date: 2022-06-26 14:50:33
  • Modify Date: 2024-01-11 17:06:08
  • Dyrk1A-IN-4 (compound 48) is a potent and orally active DYRK1A and DYRK2 inhibitor with IC50s of 2 nM and 6 nM, respectively. Dyrk1A-IN-4 has anticancer effects[1].

Name Dyrk1A-IN-4
Description Dyrk1A-IN-4 (compound 48) is a potent and orally active DYRK1A and DYRK2 inhibitor with IC50s of 2 nM and 6 nM, respectively. Dyrk1A-IN-4 has anticancer effects[1].
Related Catalog
Target

DYRK1A:2 nM (IC50)

DYRK2:6 nM (IC50)

References

[1]. Csaba Weber, et al. Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors. J Med Chem. 2021 May 27;64(10):6745-6764.

Molecular Formula C14H13F3N6
Molecular Weight 322.29
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