Dyrk1A-IN-4

Modify Date: 2024-01-11 17:06:08

Dyrk1A-IN-4 structure	Common Name	Dyrk1A-IN-4
	CAS Number	2091883-59-7	Molecular Weight	322.29
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₃F₃N₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dyrk1A-IN-4

Dyrk1A-IN-4 (compound 48) is a potent and orally active DYRK1A and DYRK2 inhibitor with IC50s of 2 nM and 6 nM, respectively. Dyrk1A-IN-4 has anticancer effects[1].

Name	Dyrk1A-IN-4

Description	Dyrk1A-IN-4 (compound 48) is a potent and orally active DYRK1A and DYRK2 inhibitor with IC50s of 2 nM and 6 nM, respectively. Dyrk1A-IN-4 has anticancer effects[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> DYRK
Target	DYRK1A:2 nM (IC50) DYRK2:6 nM (IC50)
References	[1]. Csaba Weber, et al. Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors. J Med Chem. 2021 May 27;64(10):6745-6764.

Molecular Formula	C₁₄H₁₃F₃N₆
Molecular Weight	322.29

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