127143-25-3

127143-25-3 structure

Name: FBPase-IN-2
Chemical Name: FBPase-IN-2
CAS Number: 127143-25-3
Molecular Formula: C₈H₅ClN₂O₄
Molecular Weight: 228.59
Catalog: Research Areas Metabolic Disease
Create Date: 2022-07-01 21:41:50
Modify Date: 2025-08-25 18:06:51
FBPase-IN-2 (HS36) is a potent Fructose-1,6-bisphosphatase (FBPase) covalent inhibitor with an IC50 of 0.15 μM. FBPase-IN-2 reduces glucose production in hepatocytes. FBPase-IN-2 can be used for type 2 diabetes mellitus research[1].

Name	FBPase-IN-2

Description	FBPase-IN-2 (HS36) is a potent Fructose-1,6-bisphosphatase (FBPase) covalent inhibitor with an IC50 of 0.15 μM. FBPase-IN-2 reduces glucose production in hepatocytes. FBPase-IN-2 can be used for type 2 diabetes mellitus research[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	IC50: 0.15 μM (FBPase)[1]
References	[1]. Han X, et al. Biological evaluation and SAR analysis of novel covalent inhibitors against fructose-1,6-bisphosphatase. Bioorg Med Chem. 2020 Sep 15;28(18):115624.

Molecular Formula	C₈H₅ClN₂O₄
Molecular Weight	228.59