2488764-17-4

2488764-17-4 structure

Name: FGFR-IN-7
Chemical Name: FGFR-IN-7
CAS Number: 2488764-17-4
Molecular Formula: C₁₆H₂₁ClF₂N₄O₂
Molecular Weight: 374.81
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
Create Date: 2022-07-01 20:01:19
Modify Date: 2024-01-10 18:28:03
FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-7 shows neuroprotective activity. FGFR-IN-7 improves brain exposure and reduced risk of phospholidosis. FGFR-IN-7 can be used for neurodegenerative diseases research[1].

Name	FGFR-IN-7

Description	FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-7 shows neuroprotective activity. FGFR-IN-7 improves brain exposure and reduced risk of phospholidosis. FGFR-IN-7 can be used for neurodegenerative diseases research[1].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR Research Areas >> Neurological Disease
In Vivo	FGFR-IN-7 (compound 17) (1 mg/kg, Orally, once daily for 10 days) significantly enhances recovery of coordinated movement in the in vivo rat acute stroke model[1].
References	[1]. Sakai H, et al. Fibroblast growth factor receptor modulators employing diamines with reduced phospholipidosis-inducing potential. Bioorg Med Chem. 2020 Jul 15;28(14):115562.

Molecular Formula	C₁₆H₂₁ClF₂N₄O₂
Molecular Weight	374.81