FGFR-IN-7

Modify Date: 2024-01-10 18:28:03

FGFR-IN-7 Structure
FGFR-IN-7 structure
Common Name FGFR-IN-7
CAS Number 2488764-17-4 Molecular Weight 374.81
Density N/A Boiling Point N/A
Molecular Formula C16H21ClF2N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FGFR-IN-7


FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-7 shows neuroprotective activity. FGFR-IN-7 improves brain exposure and reduced risk of phospholidosis. FGFR-IN-7 can be used for neurodegenerative diseases research[1].

 Names

Name FGFR-IN-7

 FGFR-IN-7 Biological Activity

Description FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-7 shows neuroprotective activity. FGFR-IN-7 improves brain exposure and reduced risk of phospholidosis. FGFR-IN-7 can be used for neurodegenerative diseases research[1].
Related Catalog
In Vivo FGFR-IN-7 (compound 17) (1 mg/kg, Orally, once daily for 10 days) significantly enhances recovery of coordinated movement in the in vivo rat acute stroke model[1].
References

[1]. Sakai H, et al. Fibroblast growth factor receptor modulators employing diamines with reduced phospholipidosis-inducing potential. Bioorg Med Chem. 2020 Jul 15;28(14):115562.

 Chemical & Physical Properties

Molecular Formula C16H21ClF2N4O2
Molecular Weight 374.81
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