2425804-98-2

2425804-98-2 structure
2425804-98-2 structure
  • Name: HCV-IN-37
  • Chemical Name: HCV-IN-37
  • CAS Number: 2425804-98-2
  • Molecular Formula: C31H35F2N5
  • Molecular Weight: 515.64
  • Catalog: Signaling Pathways Anti-infection HCV
  • Create Date: 2022-07-01 10:04:18
  • Modify Date: 2024-01-14 14:25:52
  • HCV-IN-37 (Compound 3d) is a potent inhibitor of HCV. HCV-IN-37 is orally available and long-lasting in rat plasma after oral administration to rats by a single dose of 15 mg/kg. The high potency of active derivative HCV-IN-37 is primarily driven by the inhibitory effect on the virus entry stage[1].

Name HCV-IN-37
Description HCV-IN-37 (Compound 3d) is a potent inhibitor of HCV. HCV-IN-37 is orally available and long-lasting in rat plasma after oral administration to rats by a single dose of 15 mg/kg. The high potency of active derivative HCV-IN-37 is primarily driven by the inhibitory effect on the virus entry stage[1].
Related Catalog
Target

EC50: 0.005 ± 0.005 μM (HCV)[1]

References

[1]. Wang Y, et al. Design, Synthesis, and Biological Evaluation of 2-((4-Bisarylmethyl-piperazin-1-yl)methyl)benzonitrile Derivatives as HCV Entry Inhibitors. J Med Chem. 2022 Feb 10;65(3):2107-2121.

Molecular Formula C31H35F2N5
Molecular Weight 515.64