2765293-30-7

2765293-30-7 structure

Name: HIV-1 protease-IN-1
Chemical Name: HIV-1 protease-IN-1
CAS Number: 2765293-30-7
Molecular Formula: C₂₅H₃₅N₃O₆S
Molecular Weight: 505.63
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2022-07-26 06:29:47
Modify Date: 2024-04-06 18:05:05
HIV-1 protease-IN-1 (Compound 1e) is a potent inhibitor of HIV-1 protease with an IC50 of 90 pM. HIV-1 protease-IN-1 demonstrates antiviral activity with EC50 value of 89 nM against B-HIV. HIV-1 protease-IN-1 exhibits activity with EC50 value of 13.59 nM against C-HIV strain ZM246. HIV-1 protease-IN-1 shows remarkable activity with EC50 value of 8.23 nM against C-HIV strain Indie[1].

Name	HIV-1 protease-IN-1

Description	HIV-1 protease-IN-1 (Compound 1e) is a potent inhibitor of HIV-1 protease with an IC50 of 90 pM. HIV-1 protease-IN-1 demonstrates antiviral activity with EC50 value of 89 nM against B-HIV. HIV-1 protease-IN-1 exhibits activity with EC50 value of 13.59 nM against C-HIV strain ZM246. HIV-1 protease-IN-1 shows remarkable activity with EC50 value of 8.23 nM against C-HIV strain Indie[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
References	[1]. Zhu M, et al. Design, synthesis and biological evaluation of protease inhibitors containing morpholine cores with remarkable potency against both HIV-1 subtypes B and C. Eur J Med Chem. 2022 Apr 5;233:114251.

Molecular Formula	C₂₅H₃₅N₃O₆S
Molecular Weight	505.63