HIV-1 protease-IN-1

Modify Date: 2025-08-29 12:20:16

HIV-1 protease-IN-1 Structure
HIV-1 protease-IN-1 structure
Common Name HIV-1 protease-IN-1
CAS Number 2765293-30-7 Molecular Weight 505.63
Density N/A Boiling Point N/A
Molecular Formula C25H35N3O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIV-1 protease-IN-1


HIV-1 protease-IN-1 (Compound 1e) is a potent inhibitor of HIV-1 protease with an IC50 of 90 pM. HIV-1 protease-IN-1 demonstrates antiviral activity with EC50 value of 89 nM against B-HIV. HIV-1 protease-IN-1 exhibits activity with EC50 value of 13.59 nM against C-HIV strain ZM246. HIV-1 protease-IN-1 shows remarkable activity with EC50 value of 8.23 nM against C-HIV strain Indie[1].

 Names

Name HIV-1 protease-IN-1

 HIV-1 protease-IN-1 Biological Activity

Description HIV-1 protease-IN-1 (Compound 1e) is a potent inhibitor of HIV-1 protease with an IC50 of 90 pM. HIV-1 protease-IN-1 demonstrates antiviral activity with EC50 value of 89 nM against B-HIV. HIV-1 protease-IN-1 exhibits activity with EC50 value of 13.59 nM against C-HIV strain ZM246. HIV-1 protease-IN-1 shows remarkable activity with EC50 value of 8.23 nM against C-HIV strain Indie[1].
Related Catalog
References

[1]. Zhu M, et al. Design, synthesis and biological evaluation of protease inhibitors containing morpholine cores with remarkable potency against both HIV-1 subtypes B and C. Eur J Med Chem. 2022 Apr 5;233:114251.

 Chemical & Physical Properties

Molecular Formula C25H35N3O6S
Molecular Weight 505.63
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