2766352-64-9

2766352-64-9 structure

2766352-64-9 structure

Name: HL-8
Chemical Name: HL-8
CAS Number: 2766352-64-9
Molecular Formula: C₅₇H₅₉F₂N₁₁O₉S₂
Molecular Weight: 1144.27
Catalog: Signaling Pathways PI3K/Akt/mTOR PI3K
Create Date: 2022-07-01 23:51:22
Modify Date: 2024-01-17 13:32:37
HL-8 is a PROTAC molecule targeting PI3K kinase. HL-8 has a significant and complete degradation effect on PI3K kinase at a concentration of 10 μM within 8 h. HL-8 has the potential for the research of cancer diseases[1].

Name	HL-8

Description	HL-8 is a PROTAC molecule targeting PI3K kinase. HL-8 has a significant and complete degradation effect on PI3K kinase at a concentration of 10 μM within 8 h. HL-8 has the potential for the research of cancer diseases[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K
References	[1]. Wang H, et al. Design, synthesis and activity study of a novel PI3K degradation by hijacking VHL E3 ubiquitin ligase. Bioorg Med Chem. 2022 May 1;61:116707.

Molecular Formula	C₅₇H₅₉F₂N₁₁O₉S₂
Molecular Weight	1144.27