2681278-09-9

2681278-09-9 structure

Name: IRAK4-IN-10
Chemical Name: IRAK4-IN-10
CAS Number: 2681278-09-9
Molecular Formula: C₂₂H₂₄N₈
Molecular Weight: 400.48
Catalog: Signaling Pathways Immunology/Inflammation IRAK
Create Date: 2022-06-30 18:46:19
Modify Date: 2025-08-25 21:44:34
IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-10 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer[1].

Name	IRAK4-IN-10

Description	IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-10 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> IRAK Research Areas >> Inflammation/Immunology Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IRAK
Target	IRAK4:1.5 nM (IC50)
References	[1]. Sabnis RW. Novel Tricyclic Heteroaryl Compounds as IRAK4 Inhibitors for Treating Cancer, Autoimmune and Inflammatory Diseases. ACS Med Chem Lett. 2022 Feb 28;13(3):336-337.

Molecular Formula	C₂₂H₂₄N₈
Molecular Weight	400.48