1236141-96-0

1236141-96-0 structure
1236141-96-0 structure
  • Name: Microtubule inhibitor 3
  • Chemical Name: Microtubule inhibitor 3
  • CAS Number: 1236141-96-0
  • Molecular Formula: C26H23FN4O3
  • Molecular Weight: 458.48
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
  • Create Date: 2022-06-26 17:28:30
  • Modify Date: 2024-01-07 14:40:55
  • Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.

Name Microtubule inhibitor 3
Description Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.
Related Catalog
References

[1]. Ding Z,et al. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer. Bioorg Med Chem. 2020 May 15;28(10):115435.

Molecular Formula C26H23FN4O3
Molecular Weight 458.48