2416338-65-1

2416338-65-1 structure

Name: Microtubule inhibitor 7
Chemical Name: Microtubule inhibitor 7
CAS Number: 2416338-65-1
Molecular Formula: C₂₅H₁₉FN₂O₅
Molecular Weight: 446.43
Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
Create Date: 2022-07-01 11:17:20
Modify Date: 2024-01-19 10:30:08
Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.

Name	Microtubule inhibitor 7

Description	Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Ding Z,et al. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer. Bioorg Med Chem. 2020 May 15;28(10):115435.

Molecular Formula	C₂₅H₁₉FN₂O₅
Molecular Weight	446.43