2365416-53-9

2365416-53-9 structure

Name: PCSK9 modulator-2
Chemical Name: PCSK9 modulator-2
CAS Number: 2365416-53-9
Molecular Formula: C₁₇H₁₂F₂N₂
Molecular Weight: 282.29
Catalog: Research Areas Metabolic Disease
Create Date: 2022-07-19 13:17:47
Modify Date: 2024-01-12 12:12:07
PCSK9 modulator-2 (Compound 1) is a potent modulator of PCSK9 with an EC50 value of 202 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-2 has the potential for the research of hyperlipidemia[1].

Name	PCSK9 modulator-2

Description	PCSK9 modulator-2 (Compound 1) is a potent modulator of PCSK9 with an EC50 value of 202 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-2 has the potential for the research of hyperlipidemia[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Xie H, et al. From methylene bridged diindole to carbonyl linked benzimidazoleindole: Development of potent and metabolically stable PCSK9 modulators. Eur J Med Chem. 2020 Nov 15;206:112678.

Molecular Formula	C₁₇H₁₂F₂N₂
Molecular Weight	282.29