2476490-20-5

2476490-20-5 structure

Name: PCSK9 modulator-4
Chemical Name: PCSK9 modulator-4
CAS Number: 2476490-20-5
Molecular Formula: C₁₇H₁₁F₂N₃O
Molecular Weight: 311.29
Catalog: Research Areas Metabolic Disease
Create Date: 2022-07-02 20:29:47
Modify Date: 2024-01-11 16:37:22
PCSK9 modulator-4 (Compound 21) is a potent modulator of PCSK9 with an EC50 value of 0.15 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-4 has the potential for the research of hyperlipidemia[1].

Name	PCSK9 modulator-4

Description	PCSK9 modulator-4 (Compound 21) is a potent modulator of PCSK9 with an EC50 value of 0.15 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-4 has the potential for the research of hyperlipidemia[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Xie H, et al. From methylene bridged diindole to carbonyl linked benzimidazoleindole: Development of potent and metabolically stable PCSK9 modulators. Eur J Med Chem. 2020 Nov 15;206:112678.

Molecular Formula	C₁₇H₁₁F₂N₃O
Molecular Weight	311.29