2419903-21-0

2419903-21-0 structure

Name: β-Lactamase-IN-7
Chemical Name: β-Lactamase-IN-7
CAS Number: 2419903-21-0
Molecular Formula: C₁₆H₁₅N₃S₂
Molecular Weight: 313.44
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2022-07-01 15:25:43
Modify Date: 2024-01-10 08:01:00
β-Lactamase-IN-7 (compound 14) is a potent VIM-Type metallo-β-lactamase inhibitor, with Kis of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively. β-Lactamase-IN-7 can effectively inhibit Klebsiella pneumoniae[1].

Name	β-Lactamase-IN-7

Description	β-Lactamase-IN-7 (compound 14) is a potent VIM-Type metallo-β-lactamase inhibitor, with Kis of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively. β-Lactamase-IN-7 can effectively inhibit Klebsiella pneumoniae[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	Ki: 1.26 μM (VIM-1), 0.54 μM (VIM-4)[1]
References	[1]. Legru A, et al. 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity. Eur J Med Chem. 2021;226:113873.

Molecular Formula	C₁₆H₁₅N₃S₂
Molecular Weight	313.44