2459489-51-9
2459489-51-9 structure
- Name: AKT-IN-13
- Chemical Name: AKT-IN-13
- CAS Number: 2459489-51-9
- Molecular Formula: C24H31ClN6O2
- Molecular Weight: 470.99
- Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
- Create Date: 2022-08-14 11:36:38
- Modify Date: 2025-10-22 16:48:07
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AKT-IN-13 (compound 4b) is a potent Akt inhibitor with IC50s of 1.6 nM, 2.4 nM and 0.3 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-13 can be used for researching anticancer[1].
| Name | AKT-IN-13 |
|---|
| Description | AKT-IN-13 (compound 4b) is a potent Akt inhibitor with IC50s of 1.6 nM, 2.4 nM and 0.3 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-13 can be used for researching anticancer[1]. |
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| Related Catalog | |
| Target |
Akt1:1.6 nM (IC50) Akt2:2.4 nM (IC50) Akt3:0.3 nM (IC50) |
| In Vitro | AKT-IN-13 (compound 4b) displays good potency in the LNCap cell line with an IC50 value of 103 nM and a high free fraction with 51.3% human plasma protein binding (PPB)[1]. |
| References |
| Molecular Formula | C24H31ClN6O2 |
|---|---|
| Molecular Weight | 470.99 |