2151067-32-0

2151067-32-0 structure

Name: Angiogenesis inhibitor 2
Chemical Name: Angiogenesis inhibitor 2
CAS Number: 2151067-32-0
Molecular Formula: C₄₂H₅₀N₄O₆S
Molecular Weight: 738.93
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-08-21 06:12:59
Modify Date: 2025-08-25 17:46:07
Angiogenesis inhibitor 2 (compound 72) is a potent angiogenesis inhibitor. Angiogenesis inhibitor 2 inhibits the proliferation of HUVEC and HCT-15 cells, with IC50 values of 1.93 and 0.21 μM. Angiogenesis inhibitor 2 induces the apoptosis of HUVEC and HCT-15 cells. Angiogenesis inhibitor 2 shows anticancer activity, and suppresses the invasion of cancer cells. Angiogenesis inhibitor 2 inhibits the angiogenesis in zebrafish embryos[1].

Name	Angiogenesis inhibitor 2

Description	Angiogenesis inhibitor 2 (compound 72) is a potent angiogenesis inhibitor. Angiogenesis inhibitor 2 inhibits the proliferation of HUVEC and HCT-15 cells, with IC50 values of 1.93 and 0.21 μM. Angiogenesis inhibitor 2 induces the apoptosis of HUVEC and HCT-15 cells. Angiogenesis inhibitor 2 shows anticancer activity, and suppresses the invasion of cancer cells. Angiogenesis inhibitor 2 inhibits the angiogenesis in zebrafish embryos[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Zhang RH, et al. Discovery of tetrandrine derivatives as tumor migration, invasion and angiogenesis inhibitors. Bioorg Chem. 2020 Aug;101:104025.

Molecular Formula	C₄₂H₅₀N₄O₆S
Molecular Weight	738.93