2507759-39-7

2507759-39-7 structure

Name: Angiogenesis inhibitor 3
Chemical Name: Angiogenesis inhibitor 3
CAS Number: 2507759-39-7
Molecular Formula: C₄₄H₄₂BrN₃O₉
Molecular Weight: 836.72
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-08-14 11:30:57
Modify Date: 2025-08-27 10:20:47
Angiogenesis inhibitor 3 (compound 8) is a potent angiogenesis inhibitor. Angiogenesis inhibitor 3 inhibits the proliferation of HUVEC and HCT-15 cells, with IC50 values of 1.00 and 0.71 μM. Angiogenesis inhibitor 3 induces the apoptosis of HUVEC and HCT-15 cells. Angiogenesis inhibitor 3 shows anticancer activity, and suppresses the invasion of cancer cells. Angiogenesis inhibitor 3 inhibits the angiogenesis in zebrafish embryos[1].

Name	Angiogenesis inhibitor 3

Description	Angiogenesis inhibitor 3 (compound 8) is a potent angiogenesis inhibitor. Angiogenesis inhibitor 3 inhibits the proliferation of HUVEC and HCT-15 cells, with IC50 values of 1.00 and 0.71 μM. Angiogenesis inhibitor 3 induces the apoptosis of HUVEC and HCT-15 cells. Angiogenesis inhibitor 3 shows anticancer activity, and suppresses the invasion of cancer cells. Angiogenesis inhibitor 3 inhibits the angiogenesis in zebrafish embryos[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Zhang RH, et al. Discovery of tetrandrine derivatives as tumor migration, invasion and angiogenesis inhibitors. Bioorg Chem. 2020 Aug;101:104025.

Molecular Formula	C₄₄H₄₂BrN₃O₉
Molecular Weight	836.72