2445277-57-4

2445277-57-4 structure

Name: Antifungal agent 33
Chemical Name: Antifungal agent 33
CAS Number: 2445277-57-4
Molecular Formula: C₂₁H₁₄ClN₅O₃
Molecular Weight: 419.82
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2022-08-09 21:09:07
Modify Date: 2024-01-03 15:05:09
Antifungal agent 33 (compound 4e) is a potent antifungal agent. Antifungal agent 33 exhibits remarkable antifungal activity against C. albicans, with a MIC of 16 μg/mL. Antifungal agent 33 shows potent inhibitory activity against Lanosterol 14α-demethylase (CYP51), with an IC50 of 0.19 μg/mL[1].

Name	Antifungal agent 33

Description	Antifungal agent 33 (compound 4e) is a potent antifungal agent. Antifungal agent 33 exhibits remarkable antifungal activity against C. albicans, with a MIC of 16 μg/mL. Antifungal agent 33 shows potent inhibitory activity against Lanosterol 14α-demethylase (CYP51), with an IC50 of 0.19 μg/mL[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Morcoss MM, et al. Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents. Bioorg Chem. 2020 Aug;101:103956.

Molecular Formula	C₂₁H₁₄ClN₅O₃
Molecular Weight	419.82