Antifungal agent 33

Modify Date: 2024-01-03 15:05:09

Antifungal agent 33 Structure
Antifungal agent 33 structure
Common Name Antifungal agent 33
CAS Number 2445277-57-4 Molecular Weight 419.82
Density N/A Boiling Point N/A
Molecular Formula C21H14ClN5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antifungal agent 33


Antifungal agent 33 (compound 4e) is a potent antifungal agent. Antifungal agent 33 exhibits remarkable antifungal activity against C. albicans, with a MIC of 16 μg/mL. Antifungal agent 33 shows potent inhibitory activity against Lanosterol 14α-demethylase (CYP51), with an IC50 of 0.19 μg/mL[1].

 Names

Name Antifungal agent 33

 Antifungal agent 33 Biological Activity

Description Antifungal agent 33 (compound 4e) is a potent antifungal agent. Antifungal agent 33 exhibits remarkable antifungal activity against C. albicans, with a MIC of 16 μg/mL. Antifungal agent 33 shows potent inhibitory activity against Lanosterol 14α-demethylase (CYP51), with an IC50 of 0.19 μg/mL[1].
Related Catalog
References

[1]. Morcoss MM, et al. Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents. Bioorg Chem. 2020 Aug;101:103956.

 Chemical & Physical Properties

Molecular Formula C21H14ClN5O3
Molecular Weight 419.82