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2378853-66-6

2378853-66-6 structure
2378853-66-6 structure
  • Name: CCT373566
  • Chemical Name: CCT373566
  • CAS Number: 2378853-66-6
  • Molecular Formula: C26H29ClF2N6O3
  • Molecular Weight: 547.00
  • Catalog: Signaling Pathways Apoptosis Bcl-2 Family
  • Create Date: 2022-08-16 15:40:17
  • Modify Date: 2024-09-16 10:28:12
  • CCT373566 is a potent and orally active degrader of transcriptional repressor BCL6, with an IC50 of 2.2 nM. CCT373566 shows strong antiproliferative efficacy in vitro and reduction in tumor growth in vivo[1].

Name CCT373566
Description CCT373566 is a potent and orally active degrader of transcriptional repressor BCL6, with an IC50 of 2.2 nM. CCT373566 shows strong antiproliferative efficacy in vitro and reduction in tumor growth in vivo[1].
Related Catalog
References

[1]. Huckvale R, et, al. Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo. J Med Chem. 2022 Jun 23;65(12):8191-8207.

Molecular Formula C26H29ClF2N6O3
Molecular Weight 547.00
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