1346153-47-6
1346153-47-6 structure
- Name: Ceftibuten hydrate
- Chemical Name: Ceftibuten hydrate
- CAS Number: 1346153-47-6
- Molecular Formula: C15H16N4O7S2
- Molecular Weight: 428.44
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2022-08-17 20:49:31
- Modify Date: 2024-01-13 18:41:52
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Ceftibuten (Sch39720) hydrate, an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens[1][2].
| Name | Ceftibuten hydrate |
|---|
| Description | Ceftibuten (Sch39720) hydrate, an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Ceftibuten (Sch39720) hydrate is highly active against Haemophilus influenza, Escherichia coli, Klebsiella sp., and Proteus sp. and moderately active against Serratia sp. and Streptococcus pyogenes. Ceftibuten hydrate is relatively inactive against enterococci and staphylococci and is only weakly active against Pseudomonas aeruginosa and obligate anaerobes. It is also stable in the presence of most β-lactamase-producing organisms except βBacteroides fragilis. Ceftibuten hydrate is very active against strains of the family Enterobacteriaceae (mean MIC for 90% of strains=0.25 μg/ml) but less active against Campylobacterjejuni (mean MIC for 90% of strains=16.0 μg/ml)[1]. |
| In Vivo | Ceftibuten hydrate, a biologically stableβ-lactam antibiotic, has been shown to be transported by the small peptide transport system, to have relatively high affinity for the carrier and to show clear stereoselective and proton-gradient dependent transport characteristics in rat intestinal brush-border membrane vesicles[3]. |
| References |
| Molecular Formula | C15H16N4O7S2 |
|---|---|
| Molecular Weight | 428.44 |