98530-76-8
98530-76-8 structure
- Name: Drotrecogin alfa (activated)
- Chemical Name: Drotrecogin alfa (activated)
- CAS Number: 98530-76-8
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2022-08-15 05:57:36
- Modify Date: 2025-08-22 12:49:48
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Drotrecogin alfa activated (DrotAA) is recombinant human activated protein C (APC). Drotrecogin alfa activated prevents smoke-induced increases in pulmonary microvascular permeability and proinflammatory cytokine IL-1β in rats. Drotrecogin alfa activated inhibits coagulation and inflammation and promotes fibrinolysis. Drotrecogin alfa activated can be used for severe sepsis reaearch[1][2].
| Name | Drotrecogin alfa (activated) |
|---|
| Description | Drotrecogin alfa activated (DrotAA) is recombinant human activated protein C (APC). Drotrecogin alfa activated prevents smoke-induced increases in pulmonary microvascular permeability and proinflammatory cytokine IL-1β in rats. Drotrecogin alfa activated inhibits coagulation and inflammation and promotes fibrinolysis. Drotrecogin alfa activated can be used for severe sepsis reaearch[1][2]. |
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| Related Catalog | |
| In Vivo | Drotrecogin alfa activated (0-20 mg/kg, IV immediately following smoke exposure, once) significantly attenuates smoke inhalation injury in a dose-dependent manner at 2 hours after insult. Drotrecogin alfa activated (20 mg/kg) has an improvement of the expiration phase of pulmonary dynamic compliance[2]. |
| References |
| No Any Chemical & Physical Properties |