2493976-27-3

2493976-27-3 structure

Name: Dyrk1A-IN-3
Chemical Name: Dyrk1A-IN-3
CAS Number: 2493976-27-3
Molecular Formula: C₁₈H₁₆N₆
Molecular Weight: 316.36
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK DYRK
Create Date: 2022-08-04 12:02:44
Modify Date: 2025-08-20 11:38:38
Dyrk1A-IN-3 (Compound 8b), a highly selective dual-specificity tyrosine-regulated kinase 1A (DYRK1A) inhibitor, maintains high levels of DYRK1A binding affinity (IC50=76 nM). Dyrk1A-IN-3 can be used for the research of neurodegenerative disorders such as Alzheimer’s Disease, Huntington’s Disease, and Parkinson’s Disease[1].

Name	Dyrk1A-IN-3

Description	Dyrk1A-IN-3 (Compound 8b), a highly selective dual-specificity tyrosine-regulated kinase 1A (DYRK1A) inhibitor, maintains high levels of DYRK1A binding affinity (IC50=76 nM). Dyrk1A-IN-3 can be used for the research of neurodegenerative disorders such as Alzheimer’s Disease, Huntington’s Disease, and Parkinson’s Disease[1].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> DYRK Research Areas >> Neurological Disease
References	[1]. Scott H Henderson, et al. Mining Public Domain Data to Develop Selective DYRK1A Inhibitors. ACS Med Chem Lett. 2020 Jun 30;11(8):1620-1626.

Molecular Formula	C₁₈H₁₆N₆
Molecular Weight	316.36