Dyrk1A-IN-3

Modify Date: 2025-08-20 11:38:38

Dyrk1A-IN-3 Structure
Dyrk1A-IN-3 structure
Common Name Dyrk1A-IN-3
CAS Number 2493976-27-3 Molecular Weight 316.36
Density N/A Boiling Point N/A
Molecular Formula C18H16N6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dyrk1A-IN-3


Dyrk1A-IN-3 (Compound 8b), a highly selective  dual-specificity tyrosine-regulated kinase 1A (DYRK1A) inhibitor, maintains high levels of DYRK1A binding affinity (IC50=76 nM). Dyrk1A-IN-3 can be used for the research of neurodegenerative disorders such as Alzheimer’s Disease, Huntington’s Disease, and Parkinson’s Disease[1].

 Names

Name Dyrk1A-IN-3

 Dyrk1A-IN-3 Biological Activity

Description Dyrk1A-IN-3 (Compound 8b), a highly selective  dual-specificity tyrosine-regulated kinase 1A (DYRK1A) inhibitor, maintains high levels of DYRK1A binding affinity (IC50=76 nM). Dyrk1A-IN-3 can be used for the research of neurodegenerative disorders such as Alzheimer’s Disease, Huntington’s Disease, and Parkinson’s Disease[1].
Related Catalog
References

[1]. Scott H Henderson, et al. Mining Public Domain Data to Develop Selective DYRK1A Inhibitors. ACS Med Chem Lett. 2020 Jun 30;11(8):1620-1626.

 Chemical & Physical Properties

Molecular Formula C18H16N6
Molecular Weight 316.36
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